ISIS PHARMA - FRANCE

NEOTONE Radiance SPF 50+

Depigmenting day cream with high sun protection for dark spots

18.600 KD
SKU: 25634  Grade:  GG
Key Benefits
  • Reduces Hyperpigmentation and Dark Spots
  • Inhibits Melanin Production
  • Provides High Broad-Spectrum Sun Protection (SPF 50+)
  • Prevents Formation of New Dark Spots
  • Enhances Skin Radiance and Evenness
How to use
  • Dosage: Apply once daily in the morning.
  • Method:
  • Estimated Period of Use: Visible improvements are typically observed after 8 weeks of consistent use. Continued use helps maintain results and prevent new dark spots.
Product Composition

AQUA (WATER), HOMOSALATE, DICAPRYLYL CARBONATE, BUTYLOCTYL SALICYLATE, METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL [NANO], CAPRYLIC/ CAPRIC TRIGLYCERIDE, BUTYL METHOXYDIBENZOYLMETHANE, DIISOPROPYL ADIPATE, ETHYLHEXYL METHOXYCRYLENE, NIACINAMIDE, STEARETH-21, BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE, STYRENE/ ACRYLATES COPOLYMER, GLYCERYL STEARATE, PEG-100 STEARATE, 1,2-HEXANEDIOL, SILICA, GLYCERIN, BENTONITE, DECYL GLUCOSIDE, VP/ EICOSENE COPOLYMER, XANTHAN GUM, ETHYLHEXYLGLYCERIN, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, PARFUM (FRAGRANCE), CHLORPHENESIN, SQUALANE, PEG-8 LAURATE, SODIUM LEVULINATE, CITRIC ACID, STEARALKONIUM HECTORITE, SODIUM ANISATE, POLYSORBATE 60, MELANIN, BIOSACCHARIDE GUM-4, PROPYLENE GLYCOL, PROPYLENE CARBONATE, PENTYLENE GLYCOL, SORBITAN ISOSTEARATE, GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT, TRIMETHOXYBENZYL ACETYLSINAPATE, DIACETYL BOLDINE, TOCOPHEROL

  • Safe for Adults
  • Safe for Teenagers
  • Not Safe for Children
  • Not Safe for Infants
  • Not Safe for Pregnancy
  • Not Safe for Breastfeeding

NEOTONE Radiance SPF 50+ effectively reduces hyperpigmentation and dark spots while preventing new ones by inhibiting melanin synthesis and providing high sun protection, resulting in a more even skin tone and radiant complexion.

Key Features

Niacinamide (Vitamin B3)

Anti-inflammatory, barrier-strengthening, and skin-brightening agent.

  • Reduces redness, improves skin barrier function, and evens skin tone.; Results in healthier, more resilient skin with reduced redness.

Mechanism of Action: Niacinamide inhibits the transfer of melanosomes to keratinocytes, reducing pigmentation. It also enhances ceramide synthesis, improving the skin barrier, and exhibits anti-inflammatory properties by inhibiting cytokine production.

Glycyrrhiza Glabra (Licorice) Root Extract

Skin brightening agent with anti-inflammatory properties.

  • Reduces the formation of new pigmentation.; Soothes and calms the skin.; Helps to lighten existing dark spots and prevent new ones from forming.

Mechanism of Action: Licorice root extract contains glabridin, which inhibits tyrosinase activity, reducing melanin synthesis. It also has anti-inflammatory effects that soothe the skin.

Diacetyl Boldine

Tyrosinase inhibitor for depigmentation

  • Effectively decreases melanin production.; Leads to a reduction in dark spots and more even skin tone.

Mechanism of Action: Diacetyl Boldine inhibits tyrosinase activity, the key enzyme in melanin synthesis, thereby reducing the production of melanin.

Trimethoxybenzyl Acetylsinapate (Sinapic Acid Derivative)

Antioxidant and melanin synthesis inhibitor.

  • Protects skin from oxidative damage.; Reduces melanin synthesis.; Helps to diminish existing dark spots and prevent new ones.

Mechanism of Action: Acts as an antioxidant and inhibits tyrosinase activity, reducing melanin production. It helps to protect the skin from oxidative stress that can trigger hyperpigmentation.

Melanin

Provides additional protection against blue light.

  • Shields skin from blue light damage.; Helps prevent hyperpigmentation and premature aging caused by blue light.

Mechanism of Action: Melanin absorbs high-energy visible (HEV) light, also known as blue light, protecting the skin from potential photoaging and pigmentation induced by blue light exposure.

Biosaccharide Gum-4

Forms a protective film against environmental pollutants.

  • Protects skin from environmental aggressors.; Helps maintain skin health and prevent pollution-induced damage.

Mechanism of Action: Creates a non-occlusive barrier on the skin surface that traps pollutants and prevents them from penetrating the skin.

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine (Tinosorb S)

Broad-spectrum UV filter.

  • Enhances overall sun protection with high photostability.; Ensures reliable protection during prolonged sun exposure.

Mechanism of Action: Absorbs both UVA and UVB radiation, providing comprehensive protection.

Methylene Bis-Benzotriazolyl Tetramethylbutylphenol [Nano] (Tinosorb M)

Broad-spectrum UV filter.

  • Provides comprehensive protection against a wide range of UV radiation.; Ensures high-level sun protection, reducing the risk of sunburn and long-term skin damage.

Mechanism of Action: Acts as a micropigment that absorbs, reflects, and scatters both UVA and UVB radiation.

Butyl Methoxydibenzoylmethane (Avobenzone)

UVA filter to protect against photoaging.

  • Offers broad-spectrum UVA protection, reducing the risk of premature aging.; Helps prevent wrinkles, loss of elasticity, and other signs of photoaging.

Mechanism of Action: Absorbs UVA radiation (320-400 nm), particularly UVA I (340-400 nm), preventing it from penetrating deep into the skin.

Glycerin

Humectant for skin hydration.

  • Promotes skin elasticity and aids in barrier repair.; Provides long-lasting moisturization, resulting in smoother skin.

Mechanism of Action: Glycerin attracts and retains moisture from the environment into the skin, enhancing hydration levels.

Most Common Indications

Hyperpigmentation Prevention
  • Description: Age spots, melasma, post-inflammatory hyperpigmentation..
Hyperpigmentation
  • Description: Age spots, melasma, and post-inflammatory hyperpigmentation..
Uneven Skin Tone
  • Description: Areas of the skin that appear lighter or darker than the surrounding skin..
Sun Protection for All Skin Types
  • Description: Skin exposed to sun needing protection from UV radiation..

Note to the Pharmacist

Patient Education

Selling Points

  • Dual Action Formula: Combines depigmenting agents with high sun protection to treat and prevent dark spots.
  • Unique Combination of Six Synergistic Active Ingredients: Offers a multi-targeted approach to hyperpigmentation.
  • High SPF 50+ Protection: Provides broad-spectrum UVA and UVB protection to prevent sun-induced pigmentation.
  • Protection Against Blue Light and Pollution: Contains melanin and biosaccharide gum-4 to shield skin from blue light and environmental pollutants.
  • Lightweight and Non-Greasy Texture: Absorbs quickly, suitable for daily use under makeup.
  • Dermatologically Tested: Ensures efficacy and skin compatibility for various skin types.
  • Moisturizing Formula: Enriched with glycerin to keep skin hydrated and comfortable.

Extra Notes

  • Avoid Contact with Eyes and Mucous Membranes: In case of contact, rinse thoroughly with water.
  • Skin Sensitivity Alert:
  • Reapplication Necessary: Reapply every two hours when exposed to direct sunlight, after swimming, sweating, or towel drying to maintain protection.
  • Sun Exposure Warning:
  • Do Not Apply on Broken or Irritated Skin: Avoid using on open wounds or areas of active dermatitis.
  • Keep Out of Reach of Children.